We report a fast, sensitive, real-time method to measure monobromamine, monochloramine and dichloramine using selected ion flow tube mass spectrometry (SIFT-MS). Relative rate coefficients and product distributions are reported for the reagent ions H(3)O(+) and O(2) (+). Rapid reactions with the haloamines were observed with H(3)O(+) and O(2) (+) but no fast reaction was found with NO(+). A slow reaction between NO(+) and dichloramine was observed. We demonstrate the feasibility of determining these compounds in a single human breath for which the limit of detection is approaching 10 parts per billion (ppb). We also report preliminary measurements of these compounds in the breath of individuals where the concentrations of bromamine and chloramine ranged from 10 to 150 ppb. Copyright (c) 2008 John Wiley & Sons, Ltd.


Rapid Commun Mass Spectrom. 2008 Feb 7;22(5):677-681



Senthilmohan ST, Kettle AJ, McEwan MJ, Dummer J, Edwards SJ, Wilson PF, Epton MJ.

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