We report a case of a 72-year-old man with advanced rectal cancer who refused an operation for cancer therapy. We underwent radiation therapy (40 Gy) for the purpose of suppressing tumor bleeding. Consequently, we administered S- 1 (100 mg/day) orally. As a result, the tumor has disappeared by radiation therapy and chemotherapy with S-1 for 2 years. We have recognized no side effects. This therapy seemed to be an effective treatment for poor-risk elderly patients.

Doi K, Ohchi T, Ogata K, Matsuo A, Kudoh K, Ohtao R, Sugimura H.

Dept.of Surgery, Miyazaki Prefectural Nobeoka Hospital.